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Updated June 10, 2014

Definition: A macule is a flat, distinct, colored area of skin that is less than 1 centimeter in diameter and does not include a change in skin texture or thickness. Some types of benign (non-cancerous) moles are macules, although other types of moles can be elevated off the surface of the skin and so aren't considered macules. The opposite of a macule is a "papule," which is more of a bump on the skin. Macules may be caused by various skin abnormalities and diseases.
Also Known As: patch, discoloration, spot, blemish
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